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APHRODISIAC AGENTS FROM MEDIC. Sarabjeet Singh, Ajay Singh Kushwah, Ramandeep Singh,Ramandeep Kaur

APHRODISIAC AGENTS FROM MEDIC.

Sarabjeet Singh, Ajay Singh Kushwah, Ramandeep Singh,Ramandeep Kaur

International Journal of Natural Product Science 2012: Spl Issue 1:153.

Abstract(RBIP-153)

An aphrodisiac is defined as an agent that arouses sexual desire in an individual. Erectile dysfunction (ED) or male impotence is defined as the inability of a man to achieve and maintain an erection sufficient for mutually satisfactory intercourse with his partner. ED occurs commonly in middle aged and older men. Sexual health and function are important determinants of quality of life. Erectile dysfunction is adversely affected by diabetes mellitus, antihypertensive, antipsychotic, antidepressant therapeutic drugs. Organic causes of ED like Hypogonadism, hyperprolactinaemia, and neurological disorders to overcome the problem of sexual (or) erectile dysfunction various natural aphrodisiac plants potentials are preferred. Phosphodiesterase type-5 (PDE-5) inhibitors are a new class of vasoactive drugs that have been developed for treatment of erectile dysfunction (ED) The mechanism of action involves active inhibition of the PDE-5 enzyme and resulting increase in cyclic guanosine monophosphate (cGMP) and smooth muscle relaxation. This paper presents a review of plants identified from various ethno botanical surveys and folklore medicinal survey which are source of PDE-5 inhibitors /aphrodisiac activity such as: Abelmoschus esculantus,Abrus preacatorium Linn. Abrus precatorius L. Abutilon indicum (Linn.), Acacia catechu Wild,. Acacia nilotica L. Willd. Achyranthes aspera Linn. Aconitum heterophyllum, Acorus calamus Linn. Actiniopteris radiata Sw. Adenanthera pavoninaAlchornia floribunda etc.
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