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HERBAL PLANTS: IS ANSWER FOR DIABETIC NEPHROPATHY. Akash Jain, Jasmine, Sunil Sharma and Vipin Saini

HERBAL PLANTS: IS ANSWER FOR DIABETIC NEPHROPATHY.

Akash Jain, Jasmine, Sunil Sharma and Vipin Saini

International Journal of Natural Product Science 2012: Spl Issue 1:139.

Abstract(RBIP-139)

The Prevalence of diabetes is 6.4%, affecting 285 million adults, in 2010 and will increase to 7.7% and affecting the 439 million adults by 2030. Diabetic nephropathy has been reported to occur in 25–40% of peoples with type I or type II diabetes and it increases by 6% per year. Diabetic nephropathy (DN) has long been recognized as the leading cause of end-stage renal disease and a major cause of morbidity and mortality in patients with diabetes. Diabetic nephropathy is characterized by glomerular hypertrophy, thickening of glomerular and tubular basement membranes, increased amounts of extracellular matrix (ECM) in the mesangium, and increased glomerular permeability. Oral hypoglycaemic agents like sulphonylureas and biguanides are still the major players in management of the disease but there is growing interest in herbal remedies due to side effects associated with the oral hypoglycaemic agents. The medicinal plants, besides having natural therapeutic values against various diseases and considerable works have been done on these plants to treat diabetic nephropathy, describes that the activity of medicinal plants is due to the presence of chemical constituents which show reduction in blood glucose levels.
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