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NONDESTRUCTIVE ANALYTICAL TECHNIQUES FOR PHARMACEUTICALS. Narinder Kumar, Rajesh Kumar, Chander Mohan

NONDESTRUCTIVE ANALYTICAL TECHNIQUES FOR PHARMACEUTICALS.

Narinder Kumar, Rajesh Kumar, Chander Mohan

International Journal of Natural Product Science 2012: Spl Issue 1:90.


Abstract

Ensuring quality of medicine is becoming more important and challenging now a days. The need of hour is to generate faster and smarter techniques to fulfill the requirement. Pharmaceutical analysis has adopted many such processes to deal with increasing commercial and social pressure to develop new medicines with reduced costs and improved productivity. These techniques are nondestructive, rapid as well as accurate. Some of these techniques like NIRS (Near Infrared Spectroscopy), Direct Analysis in Real Time (DART), Ultra high performance liquid chromatography (UPLC), Deep Raman spectroscopy, study of counterfeit tablets in glass bottle, the detection of powders in opaque plastic containers, and non-invasive detection of herbs in bottle are discussed here. These techniques are incentives for PAT (Process Analytical Technique). The analytical benefits of these techniques are real-time determination and potential for quantification of components. These techniques also provide business benefits of increased quality and productivity and fewer wasted batches.
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