HIGH QUALITY SCIENTIFIC CONTENT,  ONLINE OPEN ACCESS,  GLOBAL SCIENTIFIC AUDIENCE,  COST EFFECTIVE, ANY ONE CAN DOWNLOAD REPRINTS 
Spreading knowledge

Google Scholar

Google Scholar

Archives

Back 

A BRIEF OVERVIEW: MATRIX METALLOPROTEINASES AND ANGIOGENESIS. Sarbjot Kaur, Tejpratap Singh, Kalyan Sen

A BRIEF OVERVIEW: MATRIX METALLOPROTEINASES AND ANGIOGENESIS.

Sarbjot Kaur, Tejpratap Singh, Kalyan Sen

International Journal of Natural Product Science 2012: Spl Issue 1:67.

Abstract (RBIP-67)

Matrix metalloproteinase (MMPs) are a family of highly homologous zinc endopeptidases that cleave peptide bonds of the extracellular matrix proteins. MMP haveimportant roles in normal processes including development, wound healing, mammary gland, and uterine involution, but are also involved in angiogenesis, tumor growth, and metastasis.MMPs and TIMPs (Tissue inhibitors of Metalloproteinase) play a complex role in regulating angiogenesis. Angiogenesis is the process in which new vessels emerge from existing endothelial lined vessels. The understanding of the cellular events involved in angiogenesis providing novel therapeutic targets for the treatment of a variety of diseases , including cancer. This overview summarize about MMPs, TIMPs, and angiogenesis including its type, process, inhibitors and its significance in metastasis and other diseases.

Key words: Tissue inhibitors of metalloproteinase, extracellular matrix, angiogenesis
Attachments:
Time to create page: 0.15 seconds


Copyright © All rights reserved Science Instinct Publications sciipub.com