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NANOTECHNOLOGY: AN EMERGING TOOL IN ORAL CANCER DIAGNOSIS AND THERAPY. Indu Gupta, Amrinder Aman

NANOTECHNOLOGY: AN EMERGING TOOL IN ORAL CANCER DIAGNOSIS AND THERAPY

Indu Gupta, Amrinder Aman

International Journal of Natural Product Science 2012: Spl Issue 1:57.

Abstract(RBIP-57)

Controlled drug-delivery strategies have made a dramatic impact in medicine. In general, controlled-release polymer systems deliver drugs in the optimum dosage for long periods, thus increasing the efficacy of the drug, maximizing patient compliance and enhancing the ability to use highly toxic, poorly soluble or relatively unstable drugs. Nanoscale materials can be used as drug delivery vehicles to develop highly selective and effective therapeutic and diagnostic modalities. There are a number of advantages with nanoparticles. For example, nanoscale particles can travel through the blood stream without sedimentation or blockage of the microvasculature. In addition, nanoparticles can be taken up by the cells through natural means such as endocytosis. Nanoparticles have already been used to deliver drugs to target sites for cancer therapeutics or deliver imaging agents for cancer diagnostics. These vehicles can be engineered to recognize biophysical characteristics that are unique to the target cells and therefore minimize drug loss and toxicity associated with delivery to non-desired tissues. As per the side effects of chemotherapy drugs target delivery system is highly preferred and nanotechnology for chemotherapy is highly effective.

Kywords: nanoparticals
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