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NEW DRUG DELIVERY SYSTEM– A NOVEL INNOVATION. Aashima Bahl, HS Rao, Pooja Sharma, Dinesh Kumar

NEW DRUG DELIVERY SYSTEM– A NOVEL INNOVATION.

Aashima Bahl, HS Rao, Pooja Sharma, Dinesh Kumar


International Journal of Natural Product Science 2012: Spl Issue 1:26.

Abstract (RBIP-26)

Drug delivery is the method or process of administering a pharmaceutical compound to achieve a therapeutic effect in humans or animals. Drug delivery technologies modify drug release profile, ADME for the benefit of improving product efficacy and safety, as well as patient convenience and compliance. Drug release is from: diffusion, degradation, swelling, and affinity-based mechanisms. The innovative delivery of drugs would not only increase safety and efficacy levels but also improve the overall performance of the drug. It is value-added features for which companies can charge a premium due to the increased convenience they provide to patients. Macromolecular drugs, which are larger compared to conventional therapies, demand superior delivery platforms for greater efficacy. The goal of all sophisticated drug delivery systems, therefore, is to deploy medications intact to specifically targeted parts of the body through a medium that can control the therapy’s administration by means of either a physiological or chemical trigger. To achieve this goal, researchers are turning to advances in the worlds of micro- and nanotechnology. Polymeric microspheres, polymer micelles, and hydrogel-type materials have all been shown to be effective in enhancing drug targeting specificity, lowering systemic drug toxicity, improving treatment absorption rates, and providing protection for pharmaceuticals against biochemical degradation.
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