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MICROSPONGE DELIVERY SYSTEM- AN OVERVIEW. Kavita Attri, A.C.Rana, Nimarata Seth, Neha soni, Kiran Bala

MICROSPONGE DELIVERY SYSTEM- AN OVERVIEW.

Kavita Attri, A.C.Rana, Nimarata Seth, Neha soni, Kiran Bala

International Journal of Natural Product Science 2012: Spl Issue 1:22.

Abstract (RBIP 22)

Microsponges are polymeric delivery systems composed of porous microspheres. They are tiny sponge-like spherical particles with a large porous surface.It consists of macroporous beads, typically 10-25 microns in diameter, loaded with active agent. Moreover, they may enhance stability, reduce side effects and modify drug release favorably. Microsponge technology has many favorable characteristics, which make it a versatile drug delivery vehicle. In pharmaceutical industry, various controlled released dosage forms like solid formulation, semi solid formulation and topical preparation have more importance due to efficacy. When applied to the skin, the MDS releases its active ingredient on a time mode and also in response to other stimuli (rubbing, temperature, pH, etc). MDS technology is being used currently in cosmetics, over-the-counter (OTC) skin care. To control the delivery rate of active agents to a predetermined site in human body has been one of the biggest assurances that the drug remains primarily localized and does not enter the systemic circulation in significant amounts thus making it an area of research that is successively being done by the microsponge delivery system. This article thus gives an overview about the microsponge delivery System (MDS) which is a unique technology for the controlled release of topical agents.

Keywords: Micro sponge, Micro porous, rubbing.
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