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ADVERSE DRUG REACTIONS IN A PATIENT TREATED FOR CUTANEOUS LEISHMANIASIS WITH SODIUM STIBO-GLUCONATE. Ranjani Ramanujam, Padma L, Madan Mohan NT

ADVERSE DRUG REACTIONS IN A PATIENT TREATED FOR CUTANEOUS LEISHMANIASIS WITH SODIUM STIBO-GLUCONATE

Ranjani Ramanujam, Padma L, Madan Mohan NT

International Journal of Pharmacology & Toxicology Science 2013; 3(5): 29-32

Abstract

Cutaneous leishmaniasis, a parasitic, vector-borne infection is a major public health, affecting about 1.5 million people globally every year. Although this infection is generally self resolving within months, it can leave disfiguring scars or chronic ulcers, usually in areas not covered with clothing. Therefore, it is important to treat this patient population. Currently, antimonials like sodium stibogluconate are considered as first-line therapy; however, their use is limited by the significant adverse drug reactions. Here we present a case study, where a patient diagnosed with cutaneous leishmaniasis after travelling to the Middle-East. She was being treated with sodium stibogluconate developed severe adverse drug reactions, which required discontinuation of therapy, supportive treatment and subsequent alternate therapy for the treatment of the infection.

Keywords: Adverse drug reactions, cutaneous leishmaniasis, miltefosine, sodium stibogluconate
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