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ALZHEIMER DISEASE AND OXIDATIVE STRESS. Manveen Bhardwaj, BV Krishna Reddy, Neha Machhan, Gursimranpreet Singh, Ankit Dhir

ALZHEIMER DISEASE AND OXIDATIVE STRESS.

Manveen Bhardwaj, BV Krishna Reddy, Neha Machhan, Gursimranpreet Singh, Ankit Dhir

International Journal of Pharmacology & Toxicology Science 2013; 3(4): 30-39

Abstract

Alzheimer disease is a neurodegenerative disorders characterized by the loss of memory and cognitive function. There are number of factors which cause the free radical formation which ultimately cause the oxidative stress. Oxidative stress plays a great role in the pathophysiology of Alzheimer disease. It causes the various structural, functional and stability modifications in the neurons. Food and Drug Administration has proved number of antioxidants therapy which are having the beneficial role in the Alzheimer’s disease. Although some limitations are also observed but still these antioxidants therapies are widely used.

Keywords: Alzheimer’s disease, antioxidant therapy, free radicals, oxidative stress.
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