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EDITORIAL - VOL. 2, ISSUE 1

The global demand for antihistaminics and anticholinergic drugs is ever increasing and more stress is laid on inventing compounds with lesser adverse effects. An antihistamine decrease or eliminate the effects brought on by histamine, a chemical mediator released during allergic reactions.
Anticholinergics are a class of drugs that inhibit parasympathetic nerve impulses by selectively inhibiting the binding of the neurotransmitter acetylcholine to its receptor in nerve cells.

Plants have been used for centuries for the treatment of various allergic ailments including asthma. The scientific data available for various herbs and plants is very scarce and their bioactivities are not validated as per international standards. So to develop scientific rationale for the usage of these herbs, plants and the compounds isolated from these, various pharmacological studies, including toxicity studies need to be done so as to confirm their bioactivity and safety profile.

In this issue, one research paper presents anticholinergic and antihistaminic activities of a Labisia pumila. It has been used traditionally for treating menstrual irregularities, post artum, dysentery, rheumatism, and gennoehoea. In another research paper antidiabetic effect of Thottea gradiflora root extract has also been presented.

We hope that research information provided is of great relevance to scientific community.



Sincerely
J N Singh
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